An In-Solution Hybridisation Method for the Isolation of Pathogen DNA from Human DNA-rich Clinical Samples for Analysis by NGS

Studies on DNA from pathogenic organisms, within clinical samples, are often complicated by the presence of large amounts of host, e.g., human DNA. Isolation of pathogen DNA from these samples would improve the efficiency of next-generation sequencing (NGS) and pathogen identification. Here we descr...

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Main Authors: Smith, Miriam, Campino, Susana, Gu, Yong, Clark, Taane G., Otto, Thomas D., Maslen, Gareth, Manske, Magnus, Imwong, Mallika, Dondorp, Arjen M., Kwiatkowski, Dominic P., Quail, Michael A., Swerdlow, Harold
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837216/
https://ncbi.nlm.nih.gov/pubmed/24273626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875693X01205010018
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