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Rac signaling in breast cancer: A tale of GEFs and GAPs
Rac GTPases, small G-proteins widely implicated in tumorigenesis and metastasis, transduce signals from tyrosine-kinase, G-protein-coupled receptors (GPCRs), and integrins, and control a number of essential cellular functions including motility, adhesion, and proliferation. Deregulation of Rac signa...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312797/ https://ncbi.nlm.nih.gov/pubmed/21893191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.08.011 |
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