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Hyperlipidemia Induces Resistance to PTH Bone Anabolism in Mice via Oxidized Lipids

In hyperlipidemia, oxidized lipids accumulate in vascular tissues and trigger atherosclerosis. Such lipids also deposit in bone tissues, where they may promote osteoporosis. We found previously that oxidized lipids attenuate osteogenesis and that parathyroid hormone (PTH) bone anabolism is blunted i...

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Detalhes bibliográficos
Main Authors: Sage, Andrew P, Lu, Jinxiu, Atti, Elisa, Tetradis, Sotirios, Ascenzi, Maria-Grazia, Adams, Douglas J, Demer, Linda L, Tintut, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Bone and Mineral Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312754/
https://ncbi.nlm.nih.gov/pubmed/21611962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.312
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