Hyperlipidemia Induces Resistance to PTH Bone Anabolism in Mice via Oxidized Lipids

In hyperlipidemia, oxidized lipids accumulate in vascular tissues and trigger atherosclerosis. Such lipids also deposit in bone tissues, where they may promote osteoporosis. We found previously that oxidized lipids attenuate osteogenesis and that parathyroid hormone (PTH) bone anabolism is blunted i...

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Autors principals: Sage, Andrew P, Lu, Jinxiu, Atti, Elisa, Tetradis, Sotirios, Ascenzi, Maria-Grazia, Adams, Douglas J, Demer, Linda L, Tintut, Yin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Bone and Mineral Research 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312754/
https://ncbi.nlm.nih.gov/pubmed/21611962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.312
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