Hyperlipidemia Impairs Osteoanabolic Effects of PTH

Epidemiological and in vitro studies have suggested that hyperlipidemia/oxidized phospholipids adversely affect bone. We recently found that oxidized phospholipids attenuate PTH-induced cAMP and immediate-early gene (IEG) expression in MC3T3-E1 cells, raising concerns that clinical hyperlipidemia ma...

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Bibliographic Details
Main Authors: Huang, Michael S, Lu, Jinxiu, Ivanov, Yevgeniy, Sage, Andrew P, Tseng, Wendy, Demer, Linda L, Tintut, Yin
Format: Artigo
Language:Inglês
Published: Amer Soc Bone & Mineral Res. 2008
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576281/
https://ncbi.nlm.nih.gov/pubmed/18505371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080513
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