Chemical synthesis and biological activities of analogues of 2',5'-oligoadenylates containing 8-substituted adenosine derivatives.

The synthesis of sequence-specific 2'-5'-oligonucleotides and analogues of 2'-5' linked oligoadenylates containing 8-substituted adenosine derivatives [8-hydroxypropyladenosine (AHPr) and 8-hydroxyadenosine (AOH)] is reported. The reaction of 5'-phosphoroimidazolidate of 8-substituted adenosines und...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	Kanou, M, Ohomori, H, Takaku, H, Yokoyama, S, Kawai, G, Suhadolnik, R J, Sobol, R
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1990
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2167468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.15.4439
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