Chemical synthesis and biological activities of analogues of 2',5'-oligoadenylates containing 8-substituted adenosine derivatives.

The synthesis of sequence-specific 2'-5'-oligonucleotides and analogues of 2'-5' linked oligoadenylates containing 8-substituted adenosine derivatives [8-hydroxypropyladenosine (AHPr) and 8-hydroxyadenosine (AOH)] is reported. The reaction of 5'-phosphoroimidazolidate of 8-s...

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Hlavní autoři: Kanou, M, Ohomori, H, Takaku, H, Yokoyama, S, Kawai, G, Suhadolnik, R J, Sobol, R
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC331262/
https://ncbi.nlm.nih.gov/pubmed/2167468
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