Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

Drug resistance during chemotherapy is the major obstacle to the successful treatment of many cancers. Here, we report that inhibition of NF-E2-related factor 2 (Nrf2) may be a promising strategy to combat chemoresistance. Nrf2 is a critical transcription factor regulating a cellular protective resp...

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Jun, Sun, Zheng, Villeneuve, Nicole F., Zhang, Shirley, Zhao, Fei, Li, Yanjie, Chen, Weimin, Yi, Xiaofang, Zheng, Wenxin, Wondrak, Georg T., Wong, Pak Kin, Zhang, Donna D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
Cancer Prevention
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312612/
https://ncbi.nlm.nih.gov/pubmed/18413364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn095
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