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Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung

Background: Atypical adenomatous hyperplasia (AAH) is now recognized as a precursor lesion from which lung adenocarcinomas arise and thus represents an ideal target for studying the early genetic and epigenetic alterations associated with lung tumorigenesis such as alterations of the Wnt pathway. Me...

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Main Authors: Licchesi, Julien D.F., Westra, William H., Hooker, Craig M., Machida, Emi O., Baylin, Stephen B., Herman, James G.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312609/
https://ncbi.nlm.nih.gov/pubmed/18308762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn017
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