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The C-terminal domain of Tetrahymena thermophila telomerase holoenzyme protein p65 induces multiple structural changes in telomerase RNA

The unique cellular activity of the telomerase reverse transcriptase ribonucleoprotein (RNP) requires proper assembly of protein and RNA components into a functional complex. In the ciliate model organism Tetrahymena thermophila, the La-domain protein p65 is required for in vivo assembly of telomera...

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Hlavní autoři: Akiyama, Benjamin M., Loper, John, Najarro, Kevin, Stone, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312553/
https://ncbi.nlm.nih.gov/pubmed/22315458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031377.111
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