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A Conserved Motif in Tetrahymena thermophila Telomerase Reverse Transcriptase Is Proximal to the RNA Template and Is Essential for Boundary Definition

The ends of linear chromosomes are extended by telomerase, a ribonucleoprotein complex minimally consisting of a protein subunit called telomerase reverse transcriptase (TERT) and the telomerase RNA (TER). TERT functions by reverse transcribing a short template region of TER into telomeric DNA. Prop...

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Detalhes bibliográficos
Main Authors: Akiyama, Benjamin M., Gomez, Anastassia, Stone, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724666/
https://ncbi.nlm.nih.gov/pubmed/23760279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452425
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