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Generation of Urinary Albumin Fragments Does Not Require Proximal Tubular Uptake

Urinary albumin excretion is an important diagnostic and prognostic marker of renal function. Both animal and human urine contain large amounts of albumin fragments, but whether these fragments originate from renal tubular degradation of filtered albumin is unknown. Here, we used mice with kidneys l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Weyer, Kathrin, Nielsen, Rikke, Christensen, Erik I., Birn, Henrik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312509/
https://ncbi.nlm.nih.gov/pubmed/22282591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011101034
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