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Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats

BACKGROUND: Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins. This study examines the role of these receptors for the uptake and excretio...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Jensen, Danny, Kierulf-Lassen, Casper, Kristensen, Marie Louise Vindvad, Nørregaard, Rikke, Weyer, Kathrin, Nielsen, Rikke, Christensen, Erik Ilsø, Birn, Henrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456377/
https://ncbi.nlm.nih.gov/pubmed/28575050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178796
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