Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats

BACKGROUND: Cystatin C, a marker of kidney injury, is freely filtered in the glomeruli and reabsorbed by the proximal tubules. Megalin and cubilin are endocytic receptors essential for reabsorption of most filtered proteins. This study examines the role of these receptors for the uptake and excretio...

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發表在:PLoS One
Main Authors: Jensen, Danny, Kierulf-Lassen, Casper, Kristensen, Marie Louise Vindvad, Nørregaard, Rikke, Weyer, Kathrin, Nielsen, Rikke, Christensen, Erik Ilsø, Birn, Henrik
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5456377/
https://ncbi.nlm.nih.gov/pubmed/28575050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178796
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