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Ureteric Morphogenesis Requires Fgfr1 and Fgfr2/Frs2α Signaling in the Metanephric Mesenchyme

Conditional deletion of fibroblast growth factor receptors (Fgfrs) 1 and 2 in the metanephric mesenchyme (MM) of mice leads to a virtual absence of MM and unbranched ureteric buds that are occasionally duplex. Deletion of Fgfr2 in the MM leads to kidneys with cranially displaced ureteric buds along...

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Detalhes bibliográficos
Main Authors: Sims-Lucas, Sunder, Di Giovanni, Valeria, Schaefer, Caitlin, Cusack, Brian, Eswarakumar, Veraragavan P., Bates, Carlton M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312502/
https://ncbi.nlm.nih.gov/pubmed/22282599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011020165
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