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Biochemical analysis of the interactions of IQGAP1 C-terminal domain with CDC42
AIM: To understand the interaction of human IQGAP1 and CDC42, especially the effects of phosphorylation and a cancer-associated mutation. METHODS: Recombinant CDC42 and a novel C-terminal fragment of IQGAP1 were expressed in, and purified from, Escherichia coli. Site directed mutagenesis was used to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Co., Limited
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312201/ https://ncbi.nlm.nih.gov/pubmed/22451851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v3.i3.53 |
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