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Some essential considerations in the design and conduct of non-inferiority trials
BACKGROUND: Suppose a standard therapy (Standard) has been established to provide a clinically important reduction in risk of irreversible morbidity or mortality. In that setting, the safety and efficacy of an experimental intervention likely would be assessed in a clinical trial providing a compari...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3312046/ https://ncbi.nlm.nih.gov/pubmed/21835862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774511410994 |
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