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Marginating Dendritic Cells of the Tumor Microenvironment Cross-present Tumor Antigens and Stably Engage Tumor-Specific T cells

The nature and site of tumor-antigen presentation to immune T cells by bone-marrow-derived cells within the tumor microenvironment remains unresolved. We generated a fluorescent mouse model of spontaneous immuno-evasive breast cancer and identified a subset of myeloid cells with significant similari...

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Detalhes bibliográficos
Main Authors: Engelhardt, John J., Boldajipour, Bijan, Beemiller, Peter, Pandurangi, Priya, Sorensen, Caitlin, Werb, Zena, Egeblad, Mikala, Krummel, Matthew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311997/
https://ncbi.nlm.nih.gov/pubmed/22439936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.01.008
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