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Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu

The central and pervasive influence of cAMP on cellular functions underscores the value of stringent control of the organization of adenylyl cyclases (ACs) in the plasma membrane. Biochemical data suggest that ACs reside in membrane rafts and could compartmentalize intermediary scaffolding proteins...

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Detalhes bibliográficos
Main Authors: Ayling, Laura J., Briddon, Stephen J., Halls, Michelle L., Hammond, Gerald R. V., Vaca, Luis, Pacheco, Jonathan, Hill, Stephen J., Cooper, Dermot M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311928/
https://ncbi.nlm.nih.gov/pubmed/22399809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.091090
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