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Bub1 kinase and Sgo1 modulate chromatin structure and dynamics in response to changes in microtubule dynamics
BACKGROUND: Tension sensing of bi-oriented chromosomes is essential for the fidelity of chromosome segregation. The spindle assembly checkpoint (SAC) conveys lack of tension or attachment to the anaphase promoting complex. Components of the SAC (Bub1) phosphorylate histone H2A (S121) and recruit the...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311747/ https://ncbi.nlm.nih.gov/pubmed/22365852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.02.006 |
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