Načítá se...

Distinct antigen-presenting cells explain the cytokine bias of α-galactosylceramide variants in vivo

α-galactosylceramide (αGC) represents a new class of vaccine adjuvants and immunomodulators that stimulate NKT cells to secrete Th1 and Th2 cytokines. Synthetic variants with short or unsaturated acyl chains exhibit a striking Th2 bias in vivo but no evidence of defect in TCR signaling or stimulatio...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bai, Li, Constantinides, Michael G., Thomas, Seddon Y., Reboulet, Rachel, Meng, Fanyong, Koentgen, Frank, Teyton, Luc, Savage, Paul B, Bendelac, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311697/
https://ncbi.nlm.nih.gov/pubmed/22393151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102414
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!