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Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats

We have previously demonstrated that leptin-mediated activation of the central nervous system (CNS) melanocortin system reduces appetite and increases sympathetic activity and blood pressure (BP). In the present study we examined whether endogenous melanocortin system activation, independent of lept...

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Détails bibliographiques
Auteurs principaux: do Carmo, Jussara M., da Silva, Alexandre A., Rushing, John S., Hall, John E.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311523/
https://ncbi.nlm.nih.gov/pubmed/22204957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00392.2011
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