Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures

Recent studies have indicated that inhibitors of the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) may have direct neuroprotective actions since they reduce infarct volume after ischemia reperfusion in the brain without altering blood flow. To explore this possibility, the present study use...

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Autors principals: Renic, Marija, Kumar, Suresh N., Gebremedhin, Debebe, Florence, Matthew A., Gerges, Nashaat Z., Falck, John R., Harder, David R., Roman, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Signaling and Stress Response
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311475/
https://ncbi.nlm.nih.gov/pubmed/22245774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00340.2011
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