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Quantitative comparison of cardiac ventricular myocyte electrophysiology and response to drugs in human and nonhuman species

Explanations for arrhythmia mechanisms at the cellular level are usually based on experiments in nonhuman myocytes. However, subtle electrophysiological differences between species may lead to different rhythmic or arrhythmic cellular behaviors and drug response given the nonlinear and highly intera...

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Detalhes bibliográficos
Main Authors: O'Hara, Thomas, Rudy, Yoram
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311457/
https://ncbi.nlm.nih.gov/pubmed/22159993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00785.2011
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