Triiodothyronine increases myocardial function and pyruvate entry into the citric acid cycle after reperfusion in a model of infant cardiopulmonary bypass

Triiodothyronine (T3) supplementation improves clinical outcomes in infants after cardiac surgery using cardiopulmonary bypass by unknown mechanisms. We utilized a translational model of infant cardiopulmonary bypass to test the hypothesis that T3 modulates pyruvate entry into the citric acid cycle...

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Bibliographische Detailangaben
Hauptverfasser: Olson, Aaron K., Bouchard, Bertrand, Ning, Xue-Han, Isern, Nancy, Rosiers, Christine Des, Portman, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Energetics and Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311455/
https://ncbi.nlm.nih.gov/pubmed/22180654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00959.2011
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