Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion

Pyruvate produces inotropic responses in the adult reperfused heart. Pyruvate oxidation and anaplerotic entry into the tricarboxylic acid (TCA) cycle via carboxylation are linked to the stimulation of contractile function. The goals of this study were to determine if these metabolic pathways operate...

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Detalhes bibliográficos
Main Authors: Olson, Aaron K., Hyyti, Outi M., Cohen, Gordon A., Ning, Xue-Han, Sadilek, Martin, Isern, Nancy, Portman, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614545/
https://ncbi.nlm.nih.gov/pubmed/18849332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00739.2008
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