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Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion

Pyruvate produces inotropic responses in the adult reperfused heart. Pyruvate oxidation and anaplerotic entry into the tricarboxylic acid (TCA) cycle via carboxylation are linked to the stimulation of contractile function. The goals of this study were to determine if these metabolic pathways operate...

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Bibliografische gegevens
Hoofdauteurs: Olson, Aaron K., Hyyti, Outi M., Cohen, Gordon A., Ning, Xue-Han, Sadilek, Martin, Isern, Nancy, Portman, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614545/
https://ncbi.nlm.nih.gov/pubmed/18849332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00739.2008
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