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Bid-induced mitochondrial membrane permeabilization waves propagated by local reactive oxygen species (ROS) signaling

Bid-induced mitochondrial membrane permeabilization and cytochrome c release are central to apoptosis. It remains a mystery how tiny amounts of Bid synchronize the function of a large number of discrete organelles, particularly in mitochondria-rich cells. Looking at cell populations, the rate and la...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garcia-Perez, Cecilia, Roy, Soumya Sinha, Naghdi, Shamim, Lin, Xuena, Davies, Erika, Hajnóczky, György
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311374/
https://ncbi.nlm.nih.gov/pubmed/22393005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118244109
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