Nonmuscle myosin II exerts tension but does not translocate actin in vertebrate cytokinesis

During vertebrate cytokinesis it is thought that contractile ring constriction is driven by nonmuscle myosin II (NM II) translocation of antiparallel actin filaments. Here we report in situ, in vitro, and in vivo observations that challenge this hypothesis. Graded knockdown of NM II in cultured COS-...

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Bibliographic Details
Main Authors: Ma, Xuefei, Kovács, Mihály, Conti, Mary Anne, Wang, Aibing, Zhang, Yingfan, Sellers, James R., Adelstein, Robert S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311360/
https://ncbi.nlm.nih.gov/pubmed/22393000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116268109
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