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Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation

The recruitment of T lymphocytes during diseases such as rheumatoid arthritis is regulated by stimulation of the chemokine receptors expressed by these cells. This study was designed to assess the potential of a CXCR3-specific small-molecule agonist to inhibit the migration of activated human T cell...

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Detalhes bibliográficos
Main Authors: O'Boyle, Graeme, Fox, Christopher R. J., Walden, Hannah R., Willet, Joseph D. P., Mavin, Emily R., Hine, Dominic W., Palmer, Jeremy M., Barker, Catriona E., Lamb, Christopher A., Ali, Simi, Kirby, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311336/
https://ncbi.nlm.nih.gov/pubmed/22392992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118104109
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