Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation

The recruitment of T lymphocytes during diseases such as rheumatoid arthritis is regulated by stimulation of the chemokine receptors expressed by these cells. This study was designed to assess the potential of a CXCR3-specific small-molecule agonist to inhibit the migration of activated human T cell...

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Main Authors: O'Boyle, Graeme, Fox, Christopher R. J., Walden, Hannah R., Willet, Joseph D. P., Mavin, Emily R., Hine, Dominic W., Palmer, Jeremy M., Barker, Catriona E., Lamb, Christopher A., Ali, Simi, Kirby, John A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311336/
https://ncbi.nlm.nih.gov/pubmed/22392992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118104109
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