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LPA stimulates intestinal DRA gene transcription via LPA2 receptor, PI3K/AKT, and c-Fos-dependent pathway
DRA (downregulated in adenoma) or SLC26A3 is the major apical anion exchanger mediating Cl(−) absorption in intestinal epithelial cells. Disturbances in DRA function and expression have been implicated in diarrheal conditions such as congenital chloride diarrhea and inflammatory bowel diseases. Prev...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311307/ https://ncbi.nlm.nih.gov/pubmed/22159277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00172.2011 |
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