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The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases

We recently presented a model for site-specific protein N-glycosylation in Trypanosoma brucei whereby the TbSTT3A oligosaccharyltransferase (OST) first selectively transfers biantennary Man(5)GlcNAc(2) from the lipid-linked oligosaccharide (LLO) donor Man(5)GlcNAc(2)-PP-Dol to N-glycosylation sequon...

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Bibliographic Details
Main Authors: Izquierdo, Luis, Mehlert, Angela, Ferguson, Michael AJ
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311286/
https://ncbi.nlm.nih.gov/pubmed/22241825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cws003
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