Recombinant antibodies encoded by IGHV1-69 react with pUL32, a phosphoprotein of cytomegalovirus and B-cell superantigen

Leukemia cells from patients with chronic lymphocytic leukemia (CLL) express a highly restricted immunoglobulin heavy variable chain (IGHV) repertoire, suggesting that a limited set of antigens reacts with leukemic cells. Here, we evaluated the reactivity of a panel of different CLL recombinant anti...

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Detalhes bibliográficos
Main Authors: Steininger, Christoph, Widhopf, George F., Ghia, Emanuela M., Morello, Christopher S., Vanura, Katrina, Sanders, Rebecca, Spector, Deborah, Guiney, Don, Jäger, Ulrich, Kipps, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311256/
https://ncbi.nlm.nih.gov/pubmed/22234695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-374058
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