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VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population

Diagnosis and classification of VWD is aided by molecular analysis of the VWF gene. Because VWF polymorphisms have not been fully characterized, we performed VWF laboratory testing and gene sequencing of 184 healthy controls with a negative bleeding history. The controls included 66 (35.9%) African...

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Detalhes bibliográficos
Main Authors: Bellissimo, Daniel B., Christopherson, Pamela A., Flood, Veronica H., Gill, Joan Cox, Friedman, Kenneth D., Haberichter, Sandra L., Shapiro, Amy D., Abshire, Thomas C., Leissinger, Cindy, Hoots, W. Keith, Lusher, Jeanne M., Ragni, Margaret V., Montgomery, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311248/
https://ncbi.nlm.nih.gov/pubmed/22197721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-384610
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