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IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors

While most blood lineages are assumed to mature through a single cellular and developmental route downstream of HSCs, dendritic cells (DCs) can be derived from both myeloid and lymphoid progenitors in vivo. To determine how distinct progenitors can generate similar downstream lineages, we examined t...

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Autores principales: Becker, Amy M., Michael, Drew G., Satpathy, Ansuman T., Sciammas, Roger, Singh, Harinder, Bhattacharya, Deepta
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311244/
https://ncbi.nlm.nih.gov/pubmed/22238324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364976
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