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IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors

While most blood lineages are assumed to mature through a single cellular and developmental route downstream of HSCs, dendritic cells (DCs) can be derived from both myeloid and lymphoid progenitors in vivo. To determine how distinct progenitors can generate similar downstream lineages, we examined t...

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Main Authors: Becker, Amy M., Michael, Drew G., Satpathy, Ansuman T., Sciammas, Roger, Singh, Harinder, Bhattacharya, Deepta
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311244/
https://ncbi.nlm.nih.gov/pubmed/22238324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-364976
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