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The Transition to an Elongation Complex by T7 RNA Polymerase Is a Multistep Process()

During the transition from an initiation complex to an elongation complex (EC), T7 RNA polymerase undergoes major conformational changes that involve reorientation of a “core” subdomain as a rigid body and extensive refolding of other elements in the 266 residue N-terminal domain. The pathway and ti...

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Detalhes bibliográficos
Main Authors: Bandwar, Rajiv P., Ma, Na, Emanuel, Steven A., Anikin, Michael, Vassylyev, Dmitry G., Patel, Smita S., McAllister, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311160/
https://ncbi.nlm.nih.gov/pubmed/17548349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702589200
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