The application of methylation specific electrophoresis (MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells

BACKGROUND: Methylation of CpG sites in genomic DNA plays an important role in gene regulation and especially in gene silencing. We have reported mechanisms of epigenetic regulation for expression of mucins, which are markers of malignancy potential and early detection of human neoplasms. Epigenetic...

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Main Authors: Yokoyama, Seiya, Kitamoto, Sho, Yamada, Norishige, Houjou, Izumi, Sugai, Tamotsu, Nakamura, Shin-ichi, Arisaka, Yoshifumi, Takaori, Kyoichi, Higashi, Michiyo, Yonezawa, Suguru
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3311064/
https://ncbi.nlm.nih.gov/pubmed/22329852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-67
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