The application of methylation specific electrophoresis (MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells

<p>Abstract</p> <p>Background</p> <p>Methylation of CpG sites in genomic DNA plays an important role in gene regulation and especially in gene silencing. We have reported mechanisms of epigenetic regulation for expression of mucins, which are markers of malignancy poten...

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Detalhes bibliográficos
Main Authors: Yokoyama Seiya, Kitamoto Sho, Yamada Norishige, Houjou Izumi, Sugai Tamotsu, Nakamura Shin-ichi, Arisaka Yoshifumi, Takaori Kyoichi, Higashi Michiyo, Yonezawa Suguru
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-02-01
Colecção:BMC Cancer
Assuntos:
DNA methylation pattern
Epigenetics
Mucin
Colonic crypt
Pancreatic juice
Cancer
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/67
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