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E,E-2-Benzylidene-6-(nitrobenzylidene)cyclohexanones: Syntheses, cytotoxicity and an examination of some of their electronic, steric, and hydrophobic properties

Three series of structurally isomeric 2-benzylidene-6-(nitrobenzylidene) cyclohexanones 1–3 were prepared and evaluated against human Molt/C8 and CEM T-lymphocytes as well as murine L1210 cells. The IC(50) values of the majority of compounds are less than 10 μM and in some assays, the figures for 1d...

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Autores principales: Das, Umashankar, Doroudi, Alireza, Das, Swagatika, Bandy, Brian, Balzarini, Jan, De Clercq, Erik, Dimmock, Jonathan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310918/
https://ncbi.nlm.nih.gov/pubmed/18450457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.04.029
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