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Formation of a DNA monofunctional cis-platinum adduct cross-linking the intercalating drug N-methyl-2,7-diazapyrenium.

Our purpose was to better understand the mutual influence of cis-diamminedichloroplatinum (II) (cis-DDP) and intercalating drugs in their interactions with DNA. The present study deals with the intercalating drug N-methyl-2,7-diazapyrenium (MDAP). Two sets of experiments have been performed. In one...

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Bibliografische gegevens
Hoofdauteurs: Malinge, J M, Sip, M, Blacker, A J, Lehn, J M, Leng, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331090/
https://ncbi.nlm.nih.gov/pubmed/2374713
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