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Formation of a DNA monofunctional cis-platinum adduct cross-linking the intercalating drug N-methyl-2,7-diazapyrenium.

Our purpose was to better understand the mutual influence of cis-diamminedichloroplatinum (II) (cis-DDP) and intercalating drugs in their interactions with DNA. The present study deals with the intercalating drug N-methyl-2,7-diazapyrenium (MDAP). Two sets of experiments have been performed. In one...

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Опубликовано в::Nucleic Acids Res
Главные авторы: Malinge, J M, Sip, M, Blacker, A J, Lehn, J M, Leng, M
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 1990
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2374713/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.13.3887
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