Formation of a DNA monofunctional cis-platinum adduct cross-linking the intercalating drug N-methyl-2,7-diazapyrenium.

Our purpose was to better understand the mutual influence of cis-diamminedichloroplatinum (II) (cis-DDP) and intercalating drugs in their interactions with DNA. The present study deals with the intercalating drug N-methyl-2,7-diazapyrenium (MDAP). Two sets of experiments have been performed. In one...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Malinge, J M, Sip, M, Blacker, A J, Lehn, J M, Leng, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1990
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2374713/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.13.3887
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