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MUC1 Contributes to BPDE-Induced Human Bronchial Epithelial Cell Transformation through Facilitating EGFR Activation

Although it is well known that epidermal growth factor receptor (EGFR) is involved in lung cancer progression, whether EGFR contributes to lung epithelial cell transformation is less clear. Mucin 1 (MUC1 in human and Muc1 in animals), a glycoprotein component of airway mucus, is overexpressed in lun...

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Detalhes bibliográficos
Main Authors: Xu, Xiuling, Bai, Lang, Chen, Wenshu, Padilla, Mabel T., Liu, Yushi, Kim, Kwang Chul, Belinsky, Steven A., Lin, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310874/
https://ncbi.nlm.nih.gov/pubmed/22457794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033846
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