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Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells

Benzyl isothiocyanate (BITC), a constituent of edible cruciferous vegetables, inhibits growth of breast cancer cells but the mechanisms underlying growth inhibitory effect of BITC are not fully understood. Here, we demonstrate that BITC treatment causes FoxO1-mediated autophagic death in cultured hu...

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Detalhes bibliográficos
Main Authors: Xiao, Dong, Bommareddy, Ajay, Kim, Su-Hyeong, Sehrawat, Anuradha, Hahm, Eun-Ryeong, Singh, Shivendra V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310839/
https://ncbi.nlm.nih.gov/pubmed/22457718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032597
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