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Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells

Benzyl isothiocyanate (BITC), a constituent of edible cruciferous vegetables, inhibits growth of breast cancer cells but the mechanisms underlying growth inhibitory effect of BITC are not fully understood. Here, we demonstrate that BITC treatment causes FoxO1-mediated autophagic death in cultured hu...

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Autors principals: Xiao, Dong, Bommareddy, Ajay, Kim, Su-Hyeong, Sehrawat, Anuradha, Hahm, Eun-Ryeong, Singh, Shivendra V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310839/
https://ncbi.nlm.nih.gov/pubmed/22457718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032597
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