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Thriving under Stress: Selective Translation of HIV-1 Structural Protein mRNA during Vpr-Mediated Impairment of eIF4E Translation Activity

Translation is a regulated process and is pivotal to proper cell growth and homeostasis. All retroviruses rely on the host translational machinery for viral protein synthesis and thus may be susceptible to its perturbation in response to stress, co-infection, and/or cell cycle arrest. HIV-1 infectio...

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Detalhes bibliográficos
Main Authors: Sharma, Amit, Yilmaz, Alper, Marsh, Kim, Cochrane, Alan, Boris-Lawrie, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310836/
https://ncbi.nlm.nih.gov/pubmed/22457629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002612
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