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Widespread Site-Dependent Buffering of Human Regulatory Polymorphism

The average individual is expected to harbor thousands of variants within non-coding genomic regions involved in gene regulation. However, it is currently not possible to interpret reliably the functional consequences of genetic variation within any given transcription factor recognition sequence. T...

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Detalhes bibliográficos
Main Authors: Maurano, Matthew T., Wang, Hao, Kutyavin, Tanya, Stamatoyannopoulos, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310774/
https://ncbi.nlm.nih.gov/pubmed/22457641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002599
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