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lin-28 Controls the Succession of Cell Fate Choices via Two Distinct Activities

lin-28 is a conserved regulator of cell fate succession in animals. In Caenorhabditis elegans, it is a component of the heterochronic gene pathway that governs larval developmental timing, while its vertebrate homologs promote pluripotency and control differentiation in diverse tissues. The RNA bind...

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Détails bibliographiques
Auteurs principaux: Vadla, Bhaskar, Kemper, Kevin, Alaimo, Jennifer, Heine, Christian, Moss, Eric G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310729/
https://ncbi.nlm.nih.gov/pubmed/22457637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002588
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