Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1

Notch signaling between neighboring cells controls many cell fate decisions in metazoans both during embryogenesis and in postnatal life. Previously, we uncovered a critical role for physiological Notch signaling in suppressing osteoblast differentiation in vivo. However, the contribution of individ...

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Detalhes bibliográficos
Main Authors: Tu, Xiaolin, Chen, Jianquan, Lim, Joohyun, Karner, Courtney M., Lee, Seung-Yon, Heisig, Julia, Wiese, Cornelia, Surendran, Kameswaran, Kopan, Raphael, Gessler, Manfred, Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310726/
https://ncbi.nlm.nih.gov/pubmed/22457635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002577
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