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Astroglial NF-κB mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury

Astrocytes undergo rapid activation after injury, which is mediated in part by the transcription factor NF-κB. Consequently, activated astrocytes have been shown to induce the NF-κB regulated phagocyte NADPH oxidase (PHOX), resulting in elevated production of reactive oxygen species (ROS). We invest...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Barakat, David J., Dvoriantchikova, Galina, Ivanov, Dmitry, Shestopalov, Valery I.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310387/
https://ncbi.nlm.nih.gov/pubmed/22118627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07595.x
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