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Negative electron-transfer dissociation nLC-MS/MS facilitates the analysis of thousands of acidic peptides
We describe the first implementation of negative electron-transfer dissociation (NETD) on a hybrid ion trap-orbitrap mass spectrometer and its application to high-throughput sequencing of peptide anions. NETD – coupled with high pH separations, negative electrospray ionization (ESI), and an NETD com...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310326/ https://ncbi.nlm.nih.gov/pubmed/22335612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac203430u |
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